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Pro-inflammatory cytokines like TNF-alpha, IL-1beta, and IL-6 damage surviving nerve fibers, interfere with Schwann cell repair functions, and create a hostile environment for axonal regrowth

[DOI] [PubMed] [Google Scholar] 196.Tomomatsu N, Aoki K, Alles N, Soysa NS, Hussain A, Nakachi H, et al

Keep the pen in the refrigerator with the cartridge installed but the needle removed
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