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10.1111/j.1600-079X.2011.00878.x 184 TamuraH.JozakiM.TanabeM.ShirafutaY.MiharaY.ShinagawaM.et al (2020)
Natural Products and Drug Discovery
[DOI] [PubMed] [Google Scholar] 144.Akilov OE, Yousaf W, Lukjan SX, Verma S, Hasan T
Some specific characteristics of drugs and chemicals, such as low molecular weight, a relatively small number of hydrogen bonding sites, and increased lipophilicity, can increase the transport of these xenobiotics across the placenta barrier, which may occur through passive diffusion mechanisms [130,131]
Butyrate is also able to cross the blood-brain barrier and activate the vagus nerve and hypothalamus, thereby regulating both appetite and eating behavior [53]
