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*Correspondence: Michele Zanoni, [email protected] Arienti, [email protected] This article was submitted to Translational Medicine, a section of the journal Frontiers in Medicine Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers

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Nevertheless, some variants of HIF-3 were revealed to have negative feedback effects on HIF-1/2 [11]

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