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In France, treatment involves the administration of 1,000 g (1 mg) of cyanocobalamin per day for 1 week, followed by 1,000 g (1 mg) per week for 1 month, followed by 1,000 g (1 mg) per month, again, normally for the remainder of the patients lifetime [10]

Phase 1a: 65 healthy adults received CB4211 with no serious adverse events

Lower starting doses also help distinguish peptide effects from coincidental events

The 3.48% reduction in apoptotic cells did not reach statistical significance, though the molecular markers (caspase-3, PARP, Bcl-2/Bax) were all significant

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