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Altered DJ-1 function, its overoxidation to sulfonate form (-) at the cysteine-106 and ubiquitination, were reported in the pathophysiological response to oxidative damage and emphysema patients (17)
TNF has also been shown to increase the expression of the myosin light-chain kinase (MLCK), and inhibition of MLCK can prevent TNF induced increases in permeability in intestinal epithelial cells [15, 16]
(173) Kizildag, S
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