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If you experience any adverse reaction to your injection, most notably pain or any visible skin reaction at the spot where you injected, then you should stop use and talk with your doctor

Conflict of interests: None declared

Twenty subjects in the po MTX group were rescued at 16 weeks and were crossed over to sq MTX, while 22 subjects in the sq MTX group had their sq MTX dosage increased to 20 mg per week at that time

FIRST DOSE PFIZER REACTIONS: Has anyone else experienced EDEMA IN THE FEET/LEGS (major swelling/buildup of fluid)