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In summary, our results suggest that overexpressing MsGSTU17 in transgenic plants can mitigate salt-caused damage by scavenging reactive oxygen species and increasing GSH levels via upregulation of GST activity.

Visceral hypersensitivity, serotonin dysregulation, gut-brain axis dysfunction, and central/peripheral nervous system alterations are implicated in IBS-C pain, while FC pain is less studied and may be primarily linked to colonic distension and motility dysfunction

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