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The disease is progressive and it is marked by a gradual decline in memory, along with cognitive and executive dysfunction [76]
Seto AG, Kingston RE, Lau NC
Phase I clinical trial of curcumin, a chemopreventive agent, in patients with high-risk or pre-malignant lesions
AMPK and Nrf2 activation reportedly play key roles in mitochondrial biogenesis and antioxidant systems, and there are many studies showing that plant-derived polyphenols activate AMPK or Nrf2 [27, 28]
The brains from mice treated with intranasal GHK-Cu showed a decrease in MCP-1, a marker used to indicate inflammation [33]
