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Yet, many peopleespecially older adults, vegans, and those with certain health conditionsmay not get enough through food alone

In a Cochrane review investigated AOX supplementation protocols for male subfertility, focusing on active substances including carnitines, coenzyme Q10, selenium, zinc, vitamins C and E, and carotenoids

However, these approaches face critical delivery challenges, including poor tumor penetration, rapid systemic clearance, and off-target toxicity, necessitating nanomaterials-mediated targeted delivery systems to achieve tumor-specific accumulation and enhanced therapeutic precision