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It is the main by-product (via biliverdin) from the oxidation and breakdown of the haem moiety arising from red cell destruction (80%) and other proteins, such as myoglobin and catalase (20%), in the reticuloendothelial system tissue of the spleen, bone marrow and so forth

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Like the parent molecule, it contains a disulfide bond formed between two cysteine residues in the chain

Accessed at ncbi.nlm.nih.gov/books/NBK548536 on July 6, 2022

Quick Answer: Leg cramps are not listed as an official side effect of semaglutide in FDA labeling, but may occur indirectly through dehydration, electrolyte imbalances, or nutritional changes associated with treatment