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Our results suggested an in-depth investigation may be required for some rare taxa of interest before removing them in the bioinformatic pipeline

A 73-year-old patient with adult-onset type II citrullinemia successfully treated by sodium pyruvate and arginine

The inflammation patterns in chronic hepatitis B are not specific and may show significant overlap with other causes of chronic hepatitis, such as hepatitis C, autoimmune hepatitis, or drug effects

iScience 25 , 103569 (2022)

Allosteric regulation of ARs transcriptional activity The mechanistic insights reported above are consistent with allosteric regulation of transcription factor action, in which the type of DNA motif to which the factor binds and its protein and ligand interactions influence its conformational plasticity and the availability of tunable multimerization and protein interaction surfaces that control context-dependent and gene-specific transcriptional activity [78, 80]