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CRL4s: The CUL4-RING E3 ubiquitin ligases
Xrp1 and Irbp18 are BZIP transcription factors that heterodimerize to repair DNA double-stranded breaks caused by transposases near P-element sites [ 27 ], and transcripts for both genes are upregulated in old flies in our dataset
C.MartinezG.GomezG
Key mechanisms include: DNA Repair: Vitamin B12 helps make methionine for DNA repair
