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To determine whether activation of Kir6.1 in cardiomyocytes was responsible for the reduction in contractile efficacy identified in Figure 9, experiments were carried out in the presence of 10 M PNU37883A to inhibit the Kir6.1 current in ventricular myocytes in the presence of 100 M TMAO

doi: 10.1128/AEM.06035-11, PMID: [DOI] [PMC free article] [PubMed] [Google Scholar] 33

The more progressive A aggregation would be found in prodromal phase of AD referring to the mild cognitive impairment (MCI) with an impairment in at least one cognitive domain (Douglas and Scharre, 2019

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doi: 10.1097/HCR.0b013e3181f1fd65