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Between 70 to 88% of patients survive for 25 years following the onset of clinical symptoms, indicating a median time from symptom initiation to death ranging from 24 years to over 45 years
Adenosine Generated in the Bone Marrow Niche Through a CD38-Mediated Pathway Correlates with Progression of Human Myeloma

Changes often interpreted as angiogenesis may instead reflect alternative vascular phenomena such as remodeling, pericyte dropout, thickening of the basement membrane, or BBB disruption without true neovascularization (Sweeney et al

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