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Description

Nanotechnology especially has a prominent position in the area of biomedicine, and nanomedicines are being widely explored for the detection, diagnosis, and treatment of cancer ( Tumors have evolved a unique microenvironment, and typically display a more acidic condition, hypoxia, overexpressed reactive oxygen species (ROS), and glutathione (GSH) owing to their rapid proliferation and metabolism ( 2 -based nanocarrier for chemotherapeutics delivery, which could degrade and release drugs in response to overexpressed GSH ( Interestingly, the TME not only facilitates drug liberation, but could also be manipulated by metal nanomedicines ( In view of the rapid development of GSH-responsive and -exhausting metal nanomedicines in potentiating cancer therapy, we summarize and outline the recent advancements, mechanisms, prospects, and challenges in this field from different strategies (Scheme 1)

When Phase 2 pathways are adequately supported, activated metabolites from Phase 1 are safely neutralized and prepared for elimination through bile and urine

As no studies have been performed evaluating the short-term use of acetaminophen in patients on oral anticoagulants, more frequent assessment of INR may be appropriate in such circumstances

Inagaki and Yamaguchi [124] used SSS that suppressed the symptoms of anthraceous in cucumber plants and is also beneficial to cucumber plant productivity