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Nature 441, 537541
however, there are no clinical studies that have addressed this question
Triggered all-active metal organic framework: ferroptosis machinery contributes to the apoptotic photodynamic antitumor therapy
In gastric cancer cells, MR activates BNIP3 gene expression by downregulating lncRNA PVT1 expression and interacting with DNMT3, thereby activating mitophagy and inducing cell death ( In summary, methionine restriction selectively exacerbates the oxidative stress in cancer cells by targeting their antioxidant metabolic vulnerability-particularly through disrupting glutathione synthesis-thereby ultimately inducing cell death
Similar to resveratrol, H 2 S is likely a CR mimetic with potential antiaging functions mediated via SIRT1 activation
