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Many of these placebo-controlled studies have demonstrated that folic acid supplementation improved symptoms in severely depressed patients, elderly depressed and demented patients, and those with major acute depression or schizophrenia, particularly in individuals with RBC folate levels below 453 nmol/L (46)

HGF was originally discovered in liver research, but it is now recognized as a critical neurotrophic factor

Best Practice Res Clin Endocrinol Metabol 28:519631 Medeiros-Neto G, Marui S, Knobel M (2008) An outline concerning the potential use of recombinant human thyrotropin for improving radioiodine therapy of multinodular goiter

however, no appreciable changes in body weight, blood pressure, fasting blood glucose, or other lipid values were found

A., Shiloh M