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The broader picture is that the next generation of obesity treatments involves multi-target approaches, whether through single molecules activating multiple receptors (tirzepatide, retatrutide, survodutide, mazdutide) or through combination therapies pairing separate compounds (CagriSema)

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Concurrent administration of pyridoxine with these medications has been reported to lower their therapeutic levels, so monitoring and dosage adjustments of the anticonvulsant might be required if high-dose vitamin B is given

[Google Scholar] [PubMed] [CrossRef] Topcu-Tarladacalisir Y, Akpolat M, Uz YH, Kizilay G, Sapmaz-Metin M, Cerkezkayabekir A, Omurlu IK (2013)

Mater Chem
