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Succinyl-CoA is oxidized to fumarate by the succinate dehydrogenase (SDH) complex and then hydrated to malate by fumarate hydratase (FH)

D., Kim, S

Possible therapeutic effect of carvacrol on asthmatic patients: A randomized, double blind, placebo-controlled, phase II clinical trial

Optimization of lead phytochemicals in silico ADMET profiling (absorption, distribution, metabolism, excretion, and toxicity) has also been used to predict the bioavailability, metabolic stability, and toxicity profile of lead phytochemicals and improve drug-likeness and reduce the cost of experiments [149]

This mechanism uses 5,10-methyleneTHF, although, alternatively, 5,10-methyleneTHF may also be redistributed towards the methionine pathway