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A Cochrane review revealed that ~60% of patients experienced at least a 50% reduction in pain with topical NSAIDs, comparable to the relief provided by oral NSAIDs and slightly better than that achieved with a topical placebo (42)

However, studies evaluating the role of omega-3 PUFA-based nutraceuticals in the setting of thyroid disorders, reached inconclusive results [133]

Aids in the synthesis of neurotransmitters

The antinociceptive response was expressed as percentage of maximum possible effect (%MPE), calculated as %MPE = [(test control)/(10 control)] 100
