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Description
Praet SFE, Ong JH, Purdam C, Welvaert M, Lovell G, Dixon L, et al
& Bar, M
Q.et al (2017)
Results We demonstrated that this peptide-liposome-small molecule machinery targets AML and consequently induces cell apoptosis both in vitro and in vivo through three disparate mechanisms: (I) Oridonin, as a Michael acceptor molecule, inhibits GSH function through covalent bonding, triggering an initial imbalance of oxidative stress
Proper timing and open communication between patient and clinician are often what differentiate a successful therapy from a frustrating one
