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Among the 17 members of the PARP family, PARP1/2/5a/5b are known to have PARylating activity, whereas the rest (PARP3/4/6/7/8/10/11/12/14/15/16) are associated with mono-ADP-ribosylation (MARylation)

The Immunomodulatory Effect of Alpha-Lipoic Acid in Autoimmune Diseases

[DOI] [PubMed] [Google Scholar] 121.Manjunath G., Sarnak M.J., Levey A.S

In practice, while patch testing remains an important tool, particularly for occupational or refractory cases, it should not delay appropriate treatment when testing is unavailable, logistically delayed, or unlikely to yield actionable results