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Mechanistic studies reveal that SFN significantly downregulates programmed death-ligand 1 (PD-L1) expression on tumor cells through multiple mechanisms, including direct covalent modification of cysteine residues on STAT1, which inhibits its transcriptional activity and blocks IFN--induced PD-L1 expression (75)

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[54], the effects of 25 natural compounds (including luteolin) on amyloid-induced mitochondrial dysfunction in murine neuroblastoma N2a cells expressing the Swedish mutation were evaluated
Yong, K

Future research should explore the longterm impacts of floodrelated interventions on the health and wellbeing of this vulnerable population, paving the way for enhanced disaster preparedness and response strategies
