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In mammalian ovaries, the FOXO1 protein regulates atresia and follicular growth by promoting the induction of apoptosis in OGCs 123
It is the hardest of the three for the body to source in high enough quantities, especially during times of illness or high stress
Rather than directly supplying NAD+ precursors (like NMN or NR), it works by blocking an enzyme that consumes nicotinamide, theoretically preserving the substrate pool for endogenous NAD+ production
Consumption of Brazil nuts keeps inflammation in check due to the nutrients contained in the nuts, like ellagic acid and selenium
