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when glutathione falls below approximately 30% of normal, NAPQI covalently binds hepatocyte proteins, causing necrosis
FIGURE 2 As markers of oxygen-mediated protein damage, AOPPs have been identified as indicators of oxidative protein damage and proinflammatory mediators (78, 79)
Free Radical Biol Med 24:10231039
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Medium from irradiated human epithelial cells but not human fibroblasts reduces the clonogenic survival of unirradiated cells
