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Collectively, the results of these studies show that HGF/c-Met axis is an effective multifaceted tumor regulator, which could have pivotal implications on the understanding of HCC mechanisms and the improvement of therapeutics

10.1038/s41390-018-0191-9 Pediatr

By modulating pathways involved in glucose and lipid metabolism, this peptide holds potential as a therapeutic target for improving metabolic health and combating diabetes (9)

M1 macrophages are primarily characterized by enhanced glycolysis, pentose phosphate pathway activity, and fatty acid synthesis, with a disrupted tricarboxylic acid cycle leading to the accumulation of metabolites such as succinate and citrate (79) ( Figure 3 )