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Satarug SC, Gobe GA, Vesey DA, Phelps KR (2020) Cadmium and lead exposure, nephrotoxicity, and mortality

However, redox-lowering activity is not the only factor

Studies have shown that NAD switches off the genes of aging, helping to extend life span, increases endurance, improves cognitive function, and enhances cellular energy

Moreover, the senescence phenotype depends on specific pathologies or tissues, making the identification of selective markers essential for the development of new senolytic drug families

The Focal Adhesion Kinase (FAK) and paxillin are critical components of focal adhesions, which mediate cell adhesion and migration