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T2 high asthma is the most common, affecting primarily childhood and early adulthood, and is typically associated with eosinophilic inflammation, and is driven by cytokines, such as interleukins (IL)-4, IL-5, IL-13, which promote immunoglobulin E (IgE) production, eosinophil recruitment, and mast cell activation [13]

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[DOI] [PMC free article] [PubMed] [Google Scholar] 148.Peres D.A., de Oliveira C.A., da Costa M.S., Tokunaga V.K., Mota J.P., Rosado C., Consiglieri V.O., Kaneko T.M., Velasco M.V.R., Baby A.R

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Lam-Son Phan Tran is head of the Signaling Pathway Research Unit at RIKEN Center for Sustainable Resource Science, Japan