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666 Despite these insights, the clinical translation of early-generation HSP90 inhibitors has been hampered by systemic toxicity and insufficient CNS penetration

Perhaps a systematic in vivo study comparing the exogenous glutathione metabolism compared to endogenous (synthesized using either glutathione precursor amino acids or glutathione-based prodrugs) can provide compelling outcomes to settle this debate

PI3K/Akt signaling is involved in the pathogenesis of bleomycin-induced pulmonary fibrosis via regulation of epithelial-mesenchymal transition

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