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Drug Interactions Several common medications reduce B12 absorption: Metformin (diabetes) significant reduction in B12 absorption Proton pump inhibitors (Omeprazole, Pantoprazole) reduce stomach acid needed for absorption H2 blockers (Ranitidine, Famotidine) similar effect to PPIs Colchicine (gout) may reduce B12 absorption If you take any of these medications long-term, B12 supplementation is strongly recommended

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If you have a Vitamin B12 deficiency and pernicious anaemia which disrupts your ability to absorb B12 from your food, regular intramuscular injections of Vitamin B12 will bypass the need for gut absorption and deliver the vitamin directly into your bloodstream

human efficacy is unproven and individual results vary

(PMC) Does AOD-9604 raise IGF-1 like HGH