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Both formulations are administered as subcutaneous injections once weekly, but they use different delivery devices

As a result, collagen and other growth factors are released to repair the damaged areas

Brefonalol hydrochloride exhibits an optimal balance between -blockade and vasodilatory effects at low doses: it reduces blood pressure and slows heart rate, while increasing stroke volume instead of decreasing it, causing no significant elevation in peripheral resistance and increasing reactive hyperemia
