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382,383 The FAKTION phase 2 trial indicates that the AKT inhibitor capivasertib combined with fulvestrant significantly improves PFS and OS in postmenopausal women with HR+/HER2 advanced breast cancer who have previously received aromatase inhibitors therapy, particularly In the AKT pathway abnormal subgroup

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The acidic buffer changes the charges on the antibodies and on Protein A, G, or L, thereby weakening the interaction between them (Figure 2B)

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10.1016/j.physbeh.2017.10.024 241

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Antimicrob Agents Chemother 2018, 62(8)

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Erbel C, Tyka M, Helmes CM, Akhavanpoor M, Rupp G, Domschke G, et al

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