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the ligand in the conjugates of the invention is a ligand for a glutathione transporter that is expressed on endothelial cells of a blood-tissue barrier, including e.g

An imbalance between the pro-death and pro-survival proteins (also known as pro-apoptotic and anti-apoptotic proteins, respectively) can trigger downstream proteins in this pathway, leading to DNA fragmentation and cell death

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It helps absorb excess oil, brighten skin, and reduce blemishes