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Regardless of the host cell lines used, the clones selected at 50M MSX had the lowest average specific growth rate and the highest average specific production rates of toxic metabolic wastes, lactate and ammonia

Finally we present strategies involving the application of ischemic preconditioning and pharmacological agents, eg -lactam antibiotics, amitriptyline, riluzole and N-acetylcysteine, which result in the significant protection of nervous tissues against ischemia.