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Estos genes son estimulados principalmente cuando la clula debe aumentar sus sistemas de defensa ante el estrs oxidativo, ya que poseen en su promotor un sitio de reconocimiento comn para los factores de transcripcin kappa p (NF-kB), Sp-1, AP-1 AP-2, respuesta antioxidante (ARE) y elementos de respuesta electrof-lica (EpRE) (15)
10.2174/1871520616666151103113412 130 YaegashiH.IzumiK.KitagawaY.KadonoY.KonakaH.MizokamiA.et al
GluA1: 189.1 3.0 nm
Several powerful tools like CellChat [101] have been developed to analyze cell-cell communication between keratinocytes and other cell types in skin, but their application to the crosstalk with the microbiome still needs to be explored
(2)Genetic characterization of participants for common variants in one-carbon metabolism pathways (e.g., MTHFR, MTRR)
