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Thiamine deficiency induced neurochemical, neuroanatomical, and neuropsychological alterations: a reappraisal

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Liquid Chromatography (LC) separation was performed on Vanquish Core HPLC (UHPLC) and coupled to The TSQ Altis Plus mass spectrometer (Thermo Fisher Scientific) with an electrospray ionization (ESI) source

J Physiol

Therefore, noting the lack of spontaneous oxidation of free GSH between the two EDTA-treated samples stored at 80 o C, this result also suggests that the differences in GSH between the heparinized plasma (Preparation Condition 1) and deproteinized EDTA-treated plasma (Preparation Condition 2) are due to spontaneous oxidation of free GSH occurring in the heparinized plasma prior to the deproteinization process