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Usually, subcutaneous injection is adopted, and the dosage and treatment course need to be individualized

Sublingual B12 bypasses intestinal absorption issues and potential barriers caused by genetic variants, which makes it a more accessible treatment option for vitamin B12 deficiency

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Increase to 1mg daily and extend the evaluation window to 16 weeks

In our trial, vitamin B-12supplemented mothers had higher blood vitamin B-12 concentrations during pregnancy but not significantly lower MMA or tHcy blood concentrations