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10 , e1234 (2021)

The most promising IC/BPS biomarker thus far is the APF peptide, which was identified from cell-based assays showing decreased proliferative activity when exposed to IC/BPS patient urine or cellular releasates 24,25,26,27

Studied in models involving NNMT pathway activity, metabolic signaling, adipose-associated pathway research, and cellular energy regulation

Now, this is where it gets interesting for future research

FDA approval and testing Wegovy (for weight management) and Ozempic (for type 2 diabetes) went through years of clinical trials involving thousands of participants