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Sham) for Net_theta (Coefficient = 9.547, 95% CI 0.027 to 19.067, p = 0.049), and a significant effect with Scaled Time (Coefficient = 6.429, 95% CI -0.020 to 12.877, p = 0.051)

Our research group has also shown increased utilization of mitochondrial metabolites in melanoma persisters surviving numerous traditional chemotherapeutics 33 , and untargeted proteomics in our follow-up study further revealed significant upregulation of mitochondrial protein abundance during treatment 55 , supporting enhanced mitochondrial metabolic rewiring

Res 4 , 541551 (2016)

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Clement A, Menezo Y, Cohen M, Cornet D, Clement PJ