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For instance, a phase II trial in ulcerative colitis patients was mentioned in abstracts

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Conversely, lowland migrants who experience acute mountain sickness frequently demonstrate gut dysbiosis characterized by reduced microbial diversity and proliferation of opportunistic pathogens ( 2 Gut microbiota 2.1 Composition and function of gut microbiota The gut microbiota refers to the microbial communities residing in the human gastrointestinal tract, primarily composed of bacteria, archaea, fungi, and viruses, with bacteria being the main focus of research

Results We demonstrate a developmental perturbation in CCK-expressing excitatory neurons within the mPFC: their density increases sharply in early postnatal life, stabilizes during adolescence, and typically declines in adulthood in wild-type (WT) mice, yet remains persistently elevated in adult KI counterparts