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Answer: As of April 2026, 9 mg and 12 mg weekly are the doses with confirmed Phase 3 efficacy data, both from the TRIUMPH-4 readout (26.4 percent and 28.7 percent mean weight reduction at 68 weeks, respectively)

Biomolecules 14:593

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If it is as high as 18 umol/L, there are likely two MTHFR mutations
