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Depending on the desired effects, be it optimization of stem cell differentiation or labeling and tracking of implanted cells, this field includes the application of non-toxic and biodegradable collagen [167], carbon [168] and piezoelectric poly (L-lactic acid) (PLLA) nanofibers [169], graphene oxide (GONPs) [170] or superparamagnetic iron oxide nanoparticles (Fe 3 O 4 ) (SPIONs)

While there are numerous and subunits, PMNs express the 1 (CD29), 2 (CD18), and 3 (CD61) integrins (coupled with various subunits), which recognize fibronectin, fibrinogen, and collagen in vitro , respectively (Hynes, 1987)

Monoclonal antibodies (Becton Dickinson Biosciences, Franklin Lakes, NJ, United States) that were coupled to different fluorophores were used for each cell subset (anti-CD4-PE and anti-CD8-Alexa488)

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KD therapy could be a novel, nontoxic, cost-effective adjuvant therapy for cancer patients that exploits tumor metabolic weaknesses beyond glucose/insulin signaling