mitochondrial glutathione peroxidase Epilepsy, ferroptosis and dysfunction. GPX4, Glutathione Peroxidase 3 induced mitochondria-mediated

BDH1L, previously an enzyme of unknown function, shows sequence similarity to BDH1, an enzyme involved in interconverting acetoacetate and 3-hydroxybutyrate, major ketone bodies produced during caloric restriction in vertebrates [561]

2010;5:e14151

Currently, NAC is involved in numerous clinical trials for patients with metabolic disorders

DBS effectively reduces dyskinesias associated with medication use by decreasing the reliance on pharmacological treatments

Using SH-SY5Y cells exposed to high glucose concentrations to induce hyperglycemia, disruptions in glucose sensing leads to activation of the phosphorylated protein kinase B (pAkt)/GSK-3 signaling pathway, and increased expression of BACE and A42, an effect that can be reversed via pretreatment with melatonin [62]