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At the same time, AMPK can also inhibit the mTORC1 pathway, a key regulatory factor for cell growth and proliferation, and its inhibitory effect helps to control the progression of eye diseases (94)
doi: 10.1016/j.abb.2020.108672, 249
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Synthesis and stability of cyclic alpha-hydrogen nitroxides
These findings elucidate a novel MFAP2-ITGB8-FAK-ERK1/2-ETS2-CYP27A1-LXR signaling axis, significantly activated by CAFs-derived MFAP2 in both in vitro and in vivo models, contributing to immune exhaustion and tumor progression
