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To confirm that H 2 O 2 increased ROS, we used DCFH-DA to measure ROS and observed that it was significantly increased 4 h after treatment (Fig

Therefore, the introduction of nanoparticles with GSH-responsive or -depleted characteristics can effectively sensitize radiotherapy and further significantly improve the anticancer therapeutic effect

Investigating the mechanisms, and their role in the disease process, could provide insights into disease pathogenesis and reveal novel treatment targets

2012 February

The role of Nrf2 in liver fibrosis has been clarified by Lu, who showed that GCL subunits and GS are regulated byNrf2, which binds AREs present in their promoters [2] (Figure 6)
