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Description
It also influences insulin regulation, which is crucial for managing body weight and fat storage
metabolizes fats
Small molecule NNMT inhibitors as highly membrane-permeable, selective inhibitors, which reduce intracellular 1-MNA levels and prevent lipogenesis in vitro were investigated
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The investigators interpreted the findings as direct pharmacological validation of the NNMT-knockdown phenotype reported earlier in the Kraus 2014 genetic-validation study
