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These include smoking, excessive coffee or alcohol consumption, diabetes, rheumatoid arthritis, thyroid disorders, coeliac disease, Crohns disease, obesity, physical inactivity, chronic stress, and certain long term medications such as proton pump inhibitors and corticosteroids

Goats and Thiamine Thiamine, a vital component for carbohydrate metabolism and normal neural activity, plays a really important role in goat health

doi: 10.1016/j.arr.2012.10.004

These include: drugs to treat gastric disorders/reduce stomach acid , some diabetes medications , and oral contraceptives

Effects in the underlying literature are cumulative