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(2008), which is nearly equivalent to the manufacturers recommended human dose of 675 mg per day for a 60 kg adult, or 422 mg/m 2

These symptoms often overlap with those of other thyroid disorders, making it difficult to determine the exact cause and the correct course of therapy

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109 used a brush functionalization technique to create a gradient of TGF-3, decreasing in concentration from the articulating surface to the subchondral region, and likewise created a reverse gradient of BMP-2

The results showed no significant publication bias, thus enhancing the reliability and robustness of the conclusions