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Quantitative PCR (qPCR) was used to determine mRNA expression levels of genes negatively regulating ferroptosis (GPX4, SLC7A11, NRF2)

For instance, the authors found that the SLC25A1-SLC25A4 mitochondrial transporter interactome was linked to 22q11.2 gene defect

doi: 10.1007/s12032-013-0552-5 8 SnezhkinaAVKrasnovGSZaretskyARZhavoronkovANyushkoKMMoskalevAAet al

in the central nervous system, GLP-1 receptors on hypothalamic (arcuate nucleus) and hindbrain (nucleus tractus solitarius and area postrema) neurons drive the reduction in food intake that underlies weight loss

Diese Vorgnge kann man sich als Kettenreaktionen vorstellen, bei denen immer mehr reaktive Radikalverbindungen entstehen und weiterreagieren