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45 kcal% fat, 35 kcal% carbohydrate, 20 kcal% protein, Research Diets, Inc

A high serum value can still carry clinical meaning even though there is no established upper intake limit for oral B12

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The two-year study found that the supplementation improved B-vitamin status, decreased homocysteine concentrations, and reduced risk of total fractures compared to placebo (117)